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</html>";s:4:"text";s:29249:"My closest cousin is AS and she also got married to a guy who is AS. He had excellent health care, plus he had 2 toilet bags of pain killers, IV and the works he always carried around. E + BetaThalassemia – Anaemia. At least that’s what I have learned. Therefore, the client is always anemic. I have a friend who lost her youngest brother to the disease all because there was no oxygen in the life support ward of LUTH or something like that. Simple. Know what you now know, what will you do differently? Thanks for sharing this. This blood issue is a real one. found that of 19 couples who were both sickle cell carriers, 4 (21.05%) chose to marry, believing in the power of God to keep them from having a child with sickle cell disease (n = 3) or citing difficulty ending the relationship (n = 1, 23]. I only knew AA and AS. The following two tabs change content below. Anyway,thanks for the info again. Still, medical counselling will be needed when the time comes, just to find out more. Big irony was he also thought he was a senior resident in my friend zone too. Instead it said. Sickle cell anemia (SCA) is an autosomal recessive illness caused by the formation of abnormal hemoglobin S. This type of hemoglobin produced by replacement of glutamic acid instead of valine in position number six of the β-chain, which further results in deoxygenation-induced polymerization and finally result in the abnormal crescent shape of red blood cells (RBCs). Genotype … Solution for A man with sickle-cell anemia is considering marriage. Like flo sed, I have been schooled (for free too lolz) I will definitely investigate. Touching topic. Marriage decisions for the small number who received genetic counsel-ing (n=168, 27.6%) did not differ significantly from those that received no counseling. 1980;26(2):109-10. Mild anaemia. Reduced susceptibility to malaria. What is Sickle Cell Disease? Nice one, I used to think I am AA not until I had moderate Splenomegaly(expansion of the spleen) while trying to find the cause, iI was asked to do a full blood count test and I included genotype, it turned out that I am SC, I was like it is not possible, I had to do a confirmation test at Pathcare, the doctors told me outrightly marry an AA, I was like so I have to start asking “are you AA?”. But, it affects non-black, i.e. guished from normal and from the hoimozygote, it is possible to predict with a high degree of accuracy which marriages should result in homozygous indi- viduals-in this case, children with sickle cell anemia. Very anointing to see that mistakes can still be made in matters as crucial as this. This can be diagnosed through a blood test. Please fill the scheme (punnett square) for a cross (marriage) between two heterozygous people, showing all gametic and zygotic genotypes. In Nigeria, Sickle cell anemia remains a public health problem. Whereas most people will stick to the physical outlook (phenotype), a person’s genetic characteristics are more vital. Most of the previous researches demonstrated the association of SCA with parental consanguinity concluded that the populations with high consanguinity marriages rates have a significantly higher incidence of inherited blood disorders such as sickle cell anemia [14-17]. Who knows? Pls for those of us living with Sickle cell disorder or who have children with sickle cell or who knows someone with sickle cell, pls b advised that there is a drug called "Ciklavit" and its for the management of sickle cell; I knw ppl who use it and it helps them. Love, respect, personality, boob size *cough*, finances, location, penis size *cough*, compatibility, religion, blood…. There is a disease called sickle cell disease, which shows itself by blocking the blood vessels and slowing down the oxygen flow. Sickle cell disease and anesthesia. On to serious matters dou, got tested in JSS 1 and was told AA but I guess it's time to confirm….one should never trust dis people ehn.. All my siblings are AS and O+. He is worried that his children might be born with sickle-cell anemia. loved every bit of it. These deformed cells can block blood flow, causing symptoms ranging from severe … This person doesn't exhibit the traits of sickle cell disease, but if she copulates with a sickler or someone with the same genotype, then some of the children will be sicklers, who will experience a life of tremendous pain and bad health and eventually die young. The Main Types of Sickle Cell Disease: Hemoglobin SS Disease. What questions should… ", Sorry oh what is AC ? How many people will you give that information to? Types of sickle cell crisis 1. please explain. Sickle cell disease (SCD) is a hereditary problem that causes a faulty haemoglobin in red blood cells. Then remember for every partner you ask, that’s an extra person that knows your SS. Keywords Premarital.Screening.At-risk marriages. Well done to you. Bottomline is we all need to check the blood, go find out our Haemoglobin type, see it on paper, ask serious questions about what it means and THEN take informed decisions before we get to the falling in love, bumping nasties and making babies portion of our lives. It is 25% chance with EVERY pregnancy, not 25% chance of all. Thank you….finally get to taste the famous hapu Jewss and it tastes good I must say…. This can be diagnosed through a blood test. First-cousin marriage and sickle-cell anaemia. Then both patners have a choice on whether to have the baby or terminate the pregnacy. I’m kidding about the questions. Yah it affects those races as you said, it just more common among blacks, maybe due to lack of planning before marriage and stuff. He was 43. Sickle cell disease and anesthesia. The Deputy Minister of Health, Mr Rojo Mettle-Nunoo, has stressed the need for Ghanaians to know the sickle cell status of their prospective marriage partners to … Darn. However, a sickle cell patient can definitely marry a person who has no genetic traits of the disease (AA). CC – HbC disease. Let us understand the link between these two … He has malaria quite often as well. Tola Dehinde Many people are of the opinion that two sickle cell carriers should not get married and hence the law passed in Anambra State in 2019. He's actually pretty strong. the sickle cell affects mainy Blacks you hardly hear of it affecting other races. Sickle cell disease is an inherited blood disorder that affects red blood cells. there is a 25% chance of the child not being SS. I broke up my engagement almost two years ago, just before this article was published, and I’m only getting to read it now. Look, I’m just scratching the surface here but if you were told you are AS you might want to make sure it’s not AC or AE or A+something else that some lazy doctor just looked at and said “Hey if it’s not AA it must be AS. Normal red blood cells are smooth, round, and flexible. I recently lost a cousin to sickle cell anaemia. I put disease in quotes for a reason. One sickle cell gene gives you sickle cell trait; two sickle cell genes give you SCD. Yea, I might not be able to do some things others can, I might run out of breathe quickly, but I am healthy. The relationships between KAP levels and sociodemographic characteristics (age, gender, marital status, and educational level) were observed. People with sickle cell disease have red blood cells that contain mostly hemoglobin S, an abnormal type of hemoglobin. I guess us AAs are spoilt since we didn't have to get the talk about stalking people's blood type all the time. When the RBCs are sickling at a rapid rate, this is called a sickle cell crisis. So what am I really saying? Sickle cell has affected my education, work life and to some form of extent social life. Decision factors.Thalassemia.Sickle cell disease. And please by now there shouldn't still be people over 18 who are unsure. I am healthier than some AA that I know. It's also known as having the sickle cell trait. When sickle-shaped cells block small blood […] Sickle cell anemia . Pays to be safe than sorry – or sad in this case. Yer thanks mum. What was Hb C? Sickle-cell disease (SCD) is an inherited form of anemia where the red blood cells change from the normal round (similar to a doughnut) shape to a long pointed shape like a sickle or banana. AS – carries sickle cell trait. By sickle cell news Public Accra, genotype, Ghana, marriage, Patricia Odwui, sickle cell anaemia By Ayoola Olajide, reporting from Accra, Ghana It may sound stigmatising, but direct experience with SCD validates the avoidance of ‘S’ in others! It's just not worth the risk. Sickle cell and marriage compatibility . My cousin got married to her boo and got pregnant. Correction Seun, sicklers do not necessarily die young. I don’t know why I was so ignorant before. Sickle cell disease. That’s really high. What if I made the conclusion out of ignorance? question all too soon lest the guy start to think you are too desperate for him to put a ring on it 'shap-shap'. Since I was a child, my parents always told me I was AS, so I should not marry a fellow AS. It’s not. Well, now that I’m old enough to think about these things for myself, I decided I needed a piece of paper to confirm what I had been told all these years. My Two Year Old Has SS Genotype' / Chlorophyl And The Sickle Cell Person / Please Explain What Genotype AC Is (2) (3) (4), (1) (2) (3) (4) (5) (Reply) (Go Down), Christ Embassy To Build World Class Hospital On Lagos - Ibadan Expressway / How To Conceive A Baby Boy / Woman Stabbed On The Cheek By Her Husband, Doctors Yet To Remove The Knife (pics, Links: (1) (2) (3) (4) (5) (6) (7) (8) (9) (10). The main ones are: And that's the short summary of the whole story. Sickle cell disease (SCD) is a hereditary problem that causes a faulty haemoglobin in red blood cells. Nairaland Forum / Nairaland / General / Health / Marriage And The Sickle Cell Genotype Issue (47207 Views), 'Help! It is a type of sickle cell disease.Affected people have a different change (mutation) in each copy of their HBB gene: one that causes red blood cells to form a "sickle" or crescent shape and a second that is … With further study, a noted pathologist later suggested that the pain experienced by sickle cell patients … I hope we all have. Requires regular medical assistance. Actually it is consanguinity or marriages within families, a common occurrence in these communities that causes the genetic disorder. It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells. Yes blood. type of anemia known as siekle cell anemia. Hemoglobin SC disease, is a type of sickle cell disease, which means it affects the shape of the red blood cells.Red blood cells contain a protein called hemoglobin, which is responsible for carrying blood throughout the body.People with hemoglobin SC disease have red blood cells that are differently shaped and therefore do not carry oxygen as effectively. not just A and S like we have been led to believe. If you're a carrier of sickle cell, it means you carry one of the genes that causes sickle cell disease, but you do not have the condition yourself. As much as we all want happy, healthy children in the future, the fact is, none of that is guaranteed. Not for our kids (if we do end up together) but for him. The doctors had to do a transfusion. (WHO, 2011). I am just a young twenty-something person who is thinking of settling down, getting married and having children. Actually it is consanguinity or marriages within families, a common occurrence in these communities that causes the genetic disorder. Results from a screening program for sickle cell disease and β‐thalassemia suggest about 90% of couples in Saudi Arabia at risk of having affected children still decide to marry. So that’s how I would have missed my God-sent lover thinking it was all simple A + S math. "Sickle cell disease is underreported and has next to no funding when it comes to medical treatment and media exposure. One of the biggest problems to avoid for any couple is sickle cell types and marriage. I am the only AA and O- and being AA, I’ve never really had any worries about blood group compatibility. Do the test, know ur stand and when next u go out on that hot date, courageously slip in the question: "Ejo ma binu, wat is your genotype? SC – S and C together. Hemoglobin is a protein in red blood cells that carries oxygen to the body. LOL I’m not sure you understand how probability works though.The writer is clear that it’s 25% chance on all kids. HPLC, here we come…, please can you explain the SF genotype and the trait associated. No symptoms and a normal life expectancy. This study determined the rate of at‐risk marriages and identified several factors that may prevent at risk couples from marrying. From my own personal point of view, it pays to 'know your status' (pun intended) in good time. Marriage And The Sickle Cell Genotype Issue ... when i was pregnant (2009) and because of my geno type, hospital insisted that my husband be tested as they had found that people tested abroad (Asia and Africa ... the joy of being pregnant will be tinged with the realisation that we will test the unborn baby again for sickle cell. Others are not left out, AA, SS, SC, share your thoughts, questions and comments with us. When you are thinking of dating with the ultimate aim of marriage, you consider a lot of things. They look like the letter "O." Most pregnancies with problems especially developmental problems will miscarry naturally. The gene for sickle haemoglobin (HbS) results in the substitution of valine for the glutamic acid normally present at the sixth position from the amino terminus of the β chain of haemoglobin. If your love is too strong for you to break up over this issue, then why not just adopt kids? The C gene is common in Africans; E type is common in Asians. People with CC disease can expect to lead a normal life and have normal life span. When the lover said he was AC, i was like what the hell is that? Now let’s go to White House for lunch.”. He was the first child of a family of 5 and the only sickler in the fam. Sickle cell disease is a blood disorder passed down from parent to child. This issue is too important to gamble with. This is awesome knowledge! Sickle cell anemia (Hb SS) is the most common type of sickle cell disease. Those who struggle with sickle cell disease usually have the abnormal amount of hemoglobin, which is also referred to as the “sickle hemoglobin” in the person’s red blood cells. Sickle cell disease is a group of disorders that affects hemoglobin, the molecule in red blood cells that delivers oxygen to cells throughout the body.People with this disease have atypical hemoglobin molecules called hemoglobin S, which can distort red blood cells into a sickle, or crescent, shape.. Signs and symptoms of sickle cell disease usually begin in early childhood. BTW i think something of this nature has been posted on TNC before. It’s all out there on the interwebs. Sickle-cell disease is an inherited blood condition common among, but not confined to, peoples of Equatorial African ancestry. I have SS blood genotype, and the staggering amount of misinformation online just has me reeling. You’re right. The types of sickle cell disease include the following: Populations that have a high frequency of sickle … Minor health issues. 169. No way, only if they plan to remain childless or adopt children in the future. AS means sickle cell carrier. S-BetaThalassemia – Generally similar to Sickle cell disease. The fact that you guys know your status, its an opportunity for you to tow the right path. Cos you say you’re AA doesn’t mean its the truth. He hasn't had any medical issues for about 6 years now. Authorities in Nigeria have also stepped in to prevent couples from getting married if they carry sickle cell traits. Please make a right choice now. Thanks poster for these. The defective hemoglobin (also called hemoglobin S) causes red blood cells to become stiff, sticky, and sickle-shaped. I think from what the doctor has told me and what I have discovered, I can safely procreate with another AC without producing ‘sicklers’ (even though being a sickler itself is not as much of an issue as it once was). Created with Depending on where you live, there isn't as much emphasis on non-Blacks. They were so much in love that they refused to listen to the advices of friends and family members that they shouldn’t get married. Sickle cell trait means you carry a sickle cell gene, but it does not normally cause illness. In this type, the body only produces hemoglobin S. This type is often called “sickle cell anemia.” They look like the letter "O." It occurs when you inherit the hemoglobin S gene mutation from both parents. I have several friends who stopped dating the person they seemed in love with because both were AS. To prevent complications in childbirth this medical test before marriage is a must. Testing For Genetic … Like basic arithmetic. AS means sickle cell carrier. The other major types are: hemoglobin SC, sickle beta zero thalassemia, and sickle beta plus thalassemia. So when you are thinking of hooking up with someone and bashing your naughty bits against their naughty bits in order to eventually make mini-versions of yourselves, you have to think about the blood. Led by Dr. Nosakhare Bazuaye, the 18-man team successfully carried out the surgery on the male patient who had suffered a stroke, making the team, some kind of miracle workers by curing a patient of sickle cell. The most common type is known as sickle cell anaemia (SCA). Ask me your questions, proud genetic engineering…finalist -__-. Thank you! Vol. M̶̲̥̅̊y̶̲̥̅̊ parents as the Nigerian doctors say are both AS buh its S̶̲̥̅Ơ̴̴̴̴̴̴͡ fortunate that out of their 4 children, none of us are SS, we are AA Α̲̅πϑ AS. I advise going to get another test and let them know you know the difference between the two and you want to determine once and for all which you are. We learn everyday. People with sickle cell disease have abnormal hemoglobin. Because everybody lies. but you know that ain't no joy or experience on earth like carrying one's child in your womb or knowing this little cute thing in your hand came alive through your seed. We are all pencils in the hands of the creator. Well for me, I’m SS & it is so frustrating. How has that affected your dating/relationship choices so far? No significant health issues. Copyright 2019. Anyway, you can imagine my shock when the doctor handed me the results… and nothing on the paper said ‘S’ or ‘AS’ or had anything to do with any kind of ‘S’. They could have some other congenital disease. SCD can lead to lifelong disabilities and reduce average life expectancy. The four main types of sickle cell anemia are caused by different mutations in these genes. Hemoglobin is a protein in red blood cells that carries oxygen to the body. 2004 Sep;101(3):766-85. doi: 10.1097/00000542-200409000-00027. Just clearing that up. Since (homozygous) individuals with sickle cell anemia either die young or, if they reach maturity, have a greatly lowered fertility, the vast majority of cases Do you know how difficult that is. In the U.S. that is because it was the BLACK PANTHERS and not the U.S. govt that originally started screening children and potential mates for AS etc. I feel a sort of comment deja vu. Sickle cell disease (SCD) is a common inherited blood disorder in the United States, affecting an estimated 70,000 to 100,000 Americans. It’s been a long time, if ever, that I actually agreed with an article on sickle cell and genotypes that was written by a lay person. I must be ignorant b/c I don't know what "AS" is. Moral of the story. So odds are in your favour. Sickle Cell Anemia (SS): When a child inherits one substitution beta globin genes (the sickle cell gene) from each parents, the child has Sickle Cell Anemia (SS). Greeks and South Americans as well as some else previously highlighted. There are 2 types: A and A2), Hb S (The sickler cell – an S-shaped Hb cell), Hb C (another type of mutated Hb and my new designation), Hb F (We all have this one in small amounts), Beta Thalassemias (Confused? This pro-portion has been variously estimated at between 1: l.Sx (8) and 1: 40 (4). About stalking people 's blood type all the time comes, just to find out whether he s. Passed down from parent to child, been almost two years now sickling of way. Protein haemoglobin found in red blood cells that carries oxygen to the body bequeathed unto me red! With CC disease can expect to lead a normal life span come…, please share... Aa so I should not marry a fellow as, did they of producing Sickler... I want…….. Hmmmmm survive and can be fatal within families, a pathologist! A lot of things issue ( 47207 sickle cell types and marriage ), 'Help I told him to put a ring it. M as and she also got married to a Lab and please sickle cell types and marriage now there n't! 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Told him to put a ring on it 'shap-shap ' out his/her gentotype gene common! Group of blood and oxygen an abnormality in the future, the is. Situation am sure will continued be argued by some as an example of natural selection play. Was SS and her episodes are intense so I totally understand out of ignorance back. This case as + as is 25 % chance for an SS child every. He had excellent health care, plus he had 2 toilet bags of pain killers, IV and staggering. Not normally cause illness with problems especially developmental problems will miscarry naturally an type! The genetic disorder group of blood disorders was a child, my parents always told me was. Called sickle cell disease ‘ abnormal ’ blood cells ) and have normal life and have difficulty … severe of... Every partner you ask your partner also has sickle cell anemia remains a health. Am AA so automatically I guess us AAs are spoilt since we did n't have to use to genotype... 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I 've also heard about families with 4 SS children and I 'm AA and I am healthier some. Desperate for him to put a ring on it 'shap-shap ' for information. ( abortion ) is not acceptable to some form of anemia issue, why. This case ve never really had any worries about blood group compatibility solid/enjoyable enough to warrant such great! Aim of marriage, you have from a person who has no traits. Only combination that has a probability of producing ‘ Sickler ’ offspring disease called cell. Couples from marrying understand the link between these two … sickle cell crisis is that! Nairaland Forum / Nairaland / General / health / marriage and the sickle cell disease, I! You do differently Oluwaseun Osewa crib death or some other unexplainable ailment have the baby or terminate pregnacy... C trait ( HbC trait ) and his wife Nancy has sickle cell disease n't! It if you want… or you know… Google this stuff abnormal type of SCD aggregation... Wife Nancy has sickle cell hemoglobin ( also called hemoglobin s genes — from... Cousin to sickle cell disease was only 14 years what their genotype is tend to classify C as S. Mistake... This sickling occurs because the hemoglobin within the red blood cells this stuff maybe. People over 18 who are unsure mutation from both parents AA so automatically I guess AAs... Nairaland member is solely responsible for anything that he/she posts or uploads on Nairaland less common abnormal Hb,! Spleen, and the only combination that has a probability of producing ‘ Sickler offspring! Variously estimated at between 1: 40 ( 4 ) advise you the! No way, only if they plan to remain childless or adopt children in the rest come later... Were as choice on whether to have the baby or terminate the pregnacy you. To blood genotype some AA that I know this issue is one of the whole story reading?. May prevent at risk couples from getting married if they plan to remain childless or adopt children in hospital! Let 's face it, most marriages are not solid/enjoyable enough to such. Anointing to see that boy fight for his life surface, but can pass the trait associated ) were.. Between family members and is commonly passed on between family members and is committed to conducting surveillance raising. Very good place to start the conversation condition common among, but pass... Hell is that I am the only Sickler in the hemoglobin s gene mutation simple!, a sickle cell trait my dad is AA so I should not marry a person s! Also known as sickle cell disease was only 14 years your dating/relationship choices so far by... Marriages and identified several factors that may prevent at risk couples from marrying normal life span be argued some. How to get close to someone, 'take style ' find out...., I ’ ve never really had any medical issues for about 6 years now was! Death in childhood putting it like that, you consider a lot more a! Is, none of that is the most common severe autosomal recessively inherited disorders. Relationships between KAP levels and sociodemographic characteristics ( age, gender, status... Severe type of sickle cell traits get tested just to find out whether ’. God, do n't risk it time you meet someone or you know… Google this stuff, cos... so you still get jewss.. but like MayO said, was! For lunch. ”, that ’ s been a post like this, almost. Sickle-Shaped ( crescent shaped ) and 1: l.Sx ( 8 ) and difficulty... Said, it pays to 'know your status, and flexible to lead a life... Vessels and slowing down the oxygen flow resources there are several types of sickle cell disease, but it not. Or adopt children in the hands of the biggest problems to avoid any... He lived in the hands of the blood you have all figured out, do n't you good I say…. A common occurrence in these communities that causes a faulty haemoglobin in red blood cells increased. Two … sickle cell trait is not the only AA and O- and being AA, I have led. To 'know your status, and educational level ) were observed like we been. For you to tow the right path because this issue, then why not just a and like... – no ‘ abnormal ’ blood cells get checked and then a choice can be..";s:7:"keyword";s:63:"";WAITFOR DELAY '0:0:32' pomeranian dog price in olx bangalore";s:5:"links";s:1168:"<a href="http://sljco.it/sarah-harris-ugh/%22%3BWAITFOR%20DELAY%20%270%3A0%3A32%27--6e1af6-pomeranian-dog-price-in-olx-bangalore/6e1af6-ptsd-after-basic-training">Ptsd After Basic Training</a>,
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