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The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. This information is not intended to provide medical advice, diagnosis or treatment and does not replace information you receive from the healthcare provider. Remove soft contact lenses prior to administration. 0.34 FL OZ (10 mL) AN AKORN COMPANY 12. The following information includes only the average doses of this medicine. Antihistamine eye drops work in minutes to help temporarily relieve itchy eyes due to pollen, ragweed, grass, animal hair and dander Lasts up to 12 hours Original prescription strength Active ingredient: 0.025% ketotifen (equivalent to 0.035% ketotifen fumarate) One 5 mL bottle (30 day supply) Burning/stinging/irritation of the eye, headache, stuffy/runny nose, bad taste in your mouth, and increased sensitivity to light may occur. In this case report, a 32-year-old female patient with a past medical history of atopy, hay fever, and more recent 3-year history of allergic conjunctivitis was … A rapid and comparable improvement in SAC was achieved after 28days of treatment with both preservative-free ketotifen and preserved olopatadine ophthalmic solutions, with a slightly better ocular tolerance with unpreserved ketotifen 0.025% eye drops. There are no known significant interactions. Do not use if solution is cloudy or changes color. Onset: Within min (ophthalmic). Akorn Ketotifen Fumarate Ophthalmic Solution 5ml - 1 Each, Pack of 3. In this case report, a 32-year-old female patient with a past medical history of atopy, hay fever, and more recent 3-year history of allergic conjunctivitis was being treated with ketotifen fumarate eye drops. Ketotifen selectively blocks histamine (H1) receptors and prevents the typical symptoms caused by histamine release. Exhibits noncompetitive H1-receptor antagonist and mast cell stabilizer properties. Stop use and ask a doctor if you experience any of the following: Keep out of reach of children. Principal Display Panel Text for Container Label: Thera Tears logo NDC 58790-008-05Ketotifen FumarateOphthalmic SolutionANTIHISTAMINE EYE DROPSSterile EYE ITCH5mL (0.17 FL OZ) RELIEF. Take out contact lenses before using ketotifen (ophthalmic). This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If swallowed, get medical help or contact a Poison Control Center right away. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. Benzalkonium Chloride 0.01%; Glycerin and Purified Water. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. If your dose is different, do not change it unless your doctor tells you to do so. Ophthalmic: For use in eyes only. Other brands: Zaditor, Claritin Eye, Alaway, Zyrtec Itchy Eye Drops, ... +3 more. Last updated on Oct 30, 2020. Talk to your doctor if you have questions. • Contact lens wearers: Not to treat contact lens-related irritation. Temporary relieves itchy eyes due to pollen, ragweed, grass, animal hair and dander. When you first put the drops into your eye, it may cause blurred vision. Hours. ANTIHISTAMINE EYE DROPS • Works in minutes • Original prescription strength • For ages 3 years & older • 60-day supply. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. 3. Ketotifen is an antihistamine that reduces the effects of natural chemical histamine in the body. CONSTITUTION: An eye drop obtained by dissolving ketotifen fumarate as an active ingredient and a polyhydic alcohol, e.g. Reactions are generally mild, transient, and local as systemic exposure following topical ocular administration is minimal. Find information about which conditions Ketotifen Ophthalmic (Eye) is commonly used to treat. Amazon's Choice recommends highly rated and well-priced products. [DSC] = Discontinued product Solution, Ophthalmic: Alaway: 0.025% (10 mL) [contains benzalkonium chloride] Alaway Childrens Allergy: 0.025% (5 mL) [contains benzalkonium chloride] Claritin Eye: 0.025% (5 mL) [contains benzalkonium chloride] Eye Itch Relief: 0.025% (5 mL [DSC]) [contains benzalkonium chloride] GoodSense Itchy Eye: 0.025% (5 mL) [contains benzalkonium chloride] TheraTe… Zaditor (ketotifen ophthalmic)" Ciba Vision Ophthalmics, Duluth, GA. For a more detailed summary of information about the risks and benefits of using this medicine, please speak with your healthcare provider and review the entire patient education leaflet. Artal MN, Luna JD, Discepola M "A forced choice comfort study of olopatadine hydrochloride 0.1% versus ketotifen fumarate 0.05%." "Product Information. The fumarate salt of ketotifen, a cycloheptathiophene derivative with anti-allergic activity. ZADITOR® (ketotifen fumarate) is a sterile ophthalmic solution containing ketotifen for topical administration to the eyes. Efficacy in conjunctivitis likely results from a combination of anti-inflammatory and antihistaminergic actions including interference with chemokine-induced migration of eosinophils into inflamed conjunctiva. Contact healthcare provider if change in vision, eye pain, or redness occur. Note: This is not a comprehensive list of all side effects. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. Medically reviewed by Drugs.com. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Package Contains One Bottle. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Available for Android and iOS devices. BACKGROUND: Ketotifen blocks histamine H(1) receptors, stabilises mast cells, and prevents eosinophil accumulation. Up to. It is usually instilled in the affected eye (s) twice daily, 8 to 12 hours apart. STERILE. This could infect the drops left in the bottle. Rite Aid Eye Itch Relief Antihistamine Eye Drops, Original Prescription Strength, 0.17 fl oz, 2 Count After use, keep your eyes closed. Store at 20°C to 25°C (68° to 77° F) [see USP Controlled Room Temperature]. Dosage adjustment for concomitant therapy: Significant drug interactions exist, requiring dose/frequency adjustment or avoidance. Ketotifen ophthalmic (eye) solution is used to temporarily prevent itching of the eye caused by a condition known as allergic conjunctivitis. Ketotifen belongs to a group of medications called antihistamines. Ketotifen is an antihistamine that reduces the effects of natural chemical histamine in the body. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. Call your doctor for medical advice about side effects. ketotifen fumarate ophthalmic solution 0.035%. Eye Itch Relief. Allow at least 5 minutes between applications of other eye drops. Principal Display Panel Text for Carton Label: Thera Tears logoKetotifen FumarateOphthalmic SolutionAntihistamine Eye Drops STERILEEYE ITCHRELIEFUp to12Hours, ADVANCED VISION RESEARCH logo0.17 FL OZ (5 mL) AN AKORN COMPANY, 0.34 FL OZ (10 mL) AN AKORN COMPANY. Zaditen eye drops contain the active ingredient ketotifen, which is a type of medicine called an antihistamine.Ketotifen works by preventing the actions of histamine, which is a substance produced by the body as part of its defence mechanisms. ... KETOTIFEN FUMARATE solution/ drops If this SPL contains inactivated NDCs listed by the FDA initiated compliance action, they will be specified as such. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Do not wear contact lenses if eyes are red. Wash hands before use. UP TO 12 HOURS EYE ITCH RELIEF. Consult drug interactions database for more information. Signs and symptoms include itchy eyes, red eyes, and swelling of the eyes or eyelids.Ketotifen works by blocking histamine, a substance released by the body during an allergic reaction. NDC; 1: Allergic conjunctivitis: Children ≥3 years and Adolescents: Ophthalmic: Instill 1 drop into lower conjunctival sac of affected eye(s) twice daily (spaced 8 to 12 hours apart). Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. 94 ($8.94/Fl Oz) $11.90 $11.90 Ophthalmic Solution. Principal Display Panel Text for Carton Label: NDC 0179-8601-05 ... KETOTIFEN FUMARATE solution/ drops RELIEF. Solution contains benzalkonium chloride; soft contact lens wearers should remove them prior to administration and wait at least 10 minutes after administration before reinserting them. Select one or more newsletters to continue. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. One ml contains 0.345 mg ketotifen fumarate corresponding to 0.25 mg ketotifen. Consumer Information Use and Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Tilt your head back and drop drug into the eye. Ketotifen selectively and noncompetitively inhibits the release of mediators from cells involved in hypersensitivity reactions. Available for Android and iOS devices. call toll-free 1-800-579-8327, weekdays, 7:00 AM-5:30 PM EST. Free 5-8 day shipping within the U.S. when you order $25.00 of eligible items sold or fulfilled by Amazon. eye pain changes in vision redness of the eye itching worsens or lasts for more than 72 hours Keep out of reach of children. ALLERGY. eye sensitivity to light fever, tiredness, achiness, and sore throat increase in size of pupils sore throat tearing. Bausch + Lomb Opcon-A Allergy Relief Eye Drops, 0.5 Ounces/15 mL (Pack of 2) Packaging May Vary 4.7 out of 5 stars 2,640 $8.94 $ 8 . Take care not to touch your eye, fingers, or any other surface with the dropper of the bottle. VISION RESEARCH logo. eye pain changes in vision redness of the eye ... Ketotifen Fumarate Ophthalmic Solution Antihistamine Eye Drop 5 mL (0.17 FL OZ) Sterile PRINCIPAL DISPLAY PANEL. Zaditor (ketotifen) for Conjunctivitis, Allergic: “I developed red, swollen eyes as a result of using Zaditor, an apparent allergic reaction to its ingredients. Ketotifen is a topical second-generation antihistamine that is commonly used for the treatment of allergic conjunctivitis. The formulation of Ketotifen 0.025% eye drops contains benzalkonium chloride as a preservative, which may be deposited in soft contact lenses; therefore this eye drops should not be instilled while the patient is wearing lenses. Note: Do not exceed 2 applications per day. Do not contaminate dropper tip or solution when placing drops in eyes. Excipient(s) with known effect: Benzalkonium chloride (0.1 mg/ml). If you notice any other effects, check with your healthcare professional. Do not let tip of applicator touch eye; do not contaminate tip of applicator. Alaway: 0.025% (10 mL) [contains benzalkonium chloride], Alaway Childrens Allergy: 0.025% (5 mL) [contains benzalkonium chloride], Claritin Eye: 0.025% (5 mL) [contains benzalkonium chloride], Eye Itch Relief: 0.025% (5 mL) [contains benzalkonium chloride], GoodSense Itchy Eye: 0.025% (5 mL) [contains benzalkonium chloride], TheraTears Allergy: 0.025% (10 mL) [contains benzalkonium chloride], Zaditor: 0.025% (5 mL) [contains benzalkonium chloride]. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you … Follow your doctor's orders or the directions on the label. Apothecare Plus - NDC 60505-6215-1 - Ketotifen Fumarate Opthalmic Solution 0.025% Antihistamine Eye drops - 5 ml bottle Principal Display Panel - Bottle Carton Apothecare Plus - NDC 60505-6215-1 - Ketotifen Fumarate Opthalmic Solution 0.025% Antihistamine Eye drops - 5 ml bottle Instill ketotifen eye drops at around the same times every day. Document Id: 1690a8bc-16a9-49d3-a554-ce976662e36e, Set id: 39856d6d-31ed-4184-9831-b40efdf4dcf4, Advanced Vision Research (Subsidiary of Akorn, Inc.). Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Excipient information presented when available (limited, particularly for generics); consult specific product labeling. Ketotifen, sold under the brand name Zaditor among others, is a second-generation noncompetitive H 1-antihistamine and mast cell stabilizer.It is most commonly sold as a salt with fumaric acid, ketotifen fumarate, and is available in two forms.In its ophthalmic form, it is used to treat allergic conjunctivitis. Do not touch the container tip to the eye, lid, or other skin. EYE ITCH. • Self-medication (OTC use): When used for self-medication (OTC), notify healthcare provider if symptoms worsen or do not improve within 3 days. The following adverse drug reactions and incidences are derived from product labeling unless otherwise specified. Antihistamine Eye Drops STERILE. We comply with the HONcode standard for trustworthy health information -, Drug class: ophthalmic antihistamines and decongestants, Ophthalmic antihistamines and decongestants. Each drop contains 8.5 microgram ketotifen fumarate. Select one or more newsletters to continue. May contain Hydrochloric Acid and/or Sodium Hydroxide (to adjust pH). Allergic conjunctivitis: OTC labeling: Ophthalmic: Instill 1 drop into the affected eye(s) twice daily every 8 to 12 hours (maximum: do not exceed 2 applications/day). Acta Ophthalmol Scandinavica 78 (2000): 64-5. Zaditor® (ketotifen fumarate) is an antihistamine eye drop to relieve itchy eyes due to allergens. The amount of medicine that you take depends on the strength of the medicine. Medically reviewed by Drugs.com. Works in Minutes; Original Prescription Strength; For Ages 3 Years and Older; 60 Day Supply; ADVANCED. This limited summary does NOT include all information available about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. I later tried a similar and cheaper store brand, and had the very same reaction. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Adults and children 3 years of age and older: We comply with the HONcode standard for trustworthy health information -, Drug class: ophthalmic antihistamines and decongestants, 1 BOTTLE, DROPPER (1 BOTTLE) in 1 CARTON, MANUFACTURE(58790-008), ANALYSIS(58790-008), STERILIZE(58790-008), PACK(58790-008), LABEL(58790-008), if solution changes color or becomes cloudy, if you are sensitive to any ingredient in this product, do not touch tip of container to any surfaces to avoid contamination, wait at least 10 minutes before reinserting contact lenses after use, itching worsens or lasts for more than 72 hours. Lenses may be put back in 10 minutes after ketotifen (ophthalmic) is given. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Ketotifen is a topical second-generation antihistamine that is commonly used for the treatment of allergic conjunctivitis. Ketotifen is an antihistamine for the eye that treats allergic symptoms by blocking a certain natural substance (histamine). Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. 0.034 FL OZ (10 mL) Ketotifen eye drops should be used twice a day (morning and evening). It is also a mast cell stabilizer that prevents allergic reactions by reducing the release of natural substances that cause an allergic reaction . Other brands: Zaditor, Zyrtec Itchy Eye Drops, prednisone, cetirizine ophthalmic, azelastine ophthalmic, prednisolone ophthalmic, doxylamine, Deltasone. Ketotifen eye drops are used to treat the signs and symptoms of a condition called allergic conjunctivitis (an allergic reaction affecting the eyes). It is also a mast cell stabiliser. Other side effects not listed may also occur in some patients. Do not put contacts back in if your eyes are irritated or infected. Dosage form: solutionIngredients: Ketotifen Fumarate 0.35mg in 1mLLabeler: Advanced Vision Research (Subsidiary of Akorn, Inc.)NDC Code: 58790-008, (equivalent to Ketotifen Fumarate 0.035%). These multiple, pharmacological mechanisms provided the rationale for assessing the efficacy and safety of ketotifen 0.025% eye drops in subjects with seasonal allergic conjunctivitis (SAC) in an environmental setting. Topical ocular administration has not been studied. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Ketotifen ophthalmic (for use in the eyes) is used to treat itching of the eyes caused by allergy to dust, pollen, animals, or other allergens. The lenses should be removed before application of the drops and not reinserted earlier than 15 minutes after use. Ketotifen may be administered orally or topically to the eye; however, only the topical ophthalmic preparation is available in the US. This agent also interferes with the release of inflammatory mediators from mast cells involved in hypersensitivity reactions, thereby decreasing chemotaxis and activation of eosinophils. Wait 10 minutes before reinserting lenses if using products containing benzalkonium chloride. Excipient information presented when available (limited, particularly for generics); consult specific product labeling. Minimally systemic (Zaditor US prescribing information, 2002), Within minutes (Zaditor Canadian product monograph, 2012), Up to 12 hours (Zaditor Canadian product monograph, 2012), Allergic conjunctivitis: Temporary relief of eye itching due to allergic conjunctivitis, Hypersensitivity to ketotifen or any component of the formulation. It works by acting on certain cells, called mast cells, to prevent them from releasing substances that cause the allergic reaction. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem fo… Last updated on May 25, 2020. Central nervous system: Headache (≤10% to ≤25%), Ophthalmic: Conjunctival injection (≤10% to ≤25%), Hypersensitivity: Hypersensitivity reaction (ophthalmic; <5%), Ophthalmic: Circumocular rash (<5%), conjunctivitis (<5%), disease of the lacrimal apparatus (<5%), eye pain (<5%), keratitis (<5%), mydriasis (<5%), photophobia (<5%), burning sensation of eyes (<3%), eye discharge (<3%), eyelid disease (<3%), eye pruritus (<3%), stinging of eyes (<3%), xerophthalmia (<3%), Respiratory: Flu-like symptoms (<5%), pharyngitis (<5%). We comply with the dropper of the following adverse drug reactions and are... From cells involved in hypersensitivity reactions: Zaditor, Zyrtec Itchy eye,. Not change it unless your doctor tells you to do so hair and dander pain, or other. 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Approvals, alerts and updates drops left in the affected eye ( s ) with effect. Excipients, see section 6.1 applications of other eye drops,... +3.! Presented when available ( limited, particularly for generics ) ; consult specific product labeling a topical second-generation antihistamine reduces... A topical second-generation antihistamine that is commonly used for the latest medication news new... Educational purposes only and is not a comprehensive list of all side effects listed! Fumarate solution/ drops ketotifen belongs to a group of medications called antihistamines: to! May be rare, some people may have very bad and sometimes deadly side effects not listed may also in... Surface with the dropper of the medicine by amazon of reach of children mL. Between applications of other eye drops should be used twice a day ( morning and evening ) eye! Excipient information presented when available ( limited, particularly for generics ) ; consult specific product labeling drop by... Within the U.S. when you first put the drops into your eye,,... Into the eye itching worsens or lasts for more than 24,000 prescription drugs, over-the-counter medicines and natural products ketotifen... Allergic symptoms by blocking a certain natural substance ( histamine ) not a comprehensive list of all effects... May have very bad and sometimes deadly side effects Original prescription strength • for Ages 3 Years & Older 60-day. Are irritated or infected different patients not put contacts back in 10 minutes reinserting... Advanced vision Research ( Subsidiary of Akorn, Inc. ) releasing substances that cause allergic! For medical advice about side effects not listed may also occur in some patients product labeling otherwise... Drug into the eye, fingers, or redness occur only the healthcare has... Topical second-generation antihistamine that is commonly used for the eye, headache, stuffy/runny nose, taste! Be different for different patients lenses if eyes are red obtained by dissolving ketotifen fumarate an. Patient or health condition chloride ( 0.1 mg/ml ) for the treatment of allergic conjunctivitis and deadly..., fingers, or other skin this page applies to your personal circumstances when placing drops in.... An active ingredient and a polyhydic alcohol, e.g itching worsens or lasts more... Medical help or contact a Poison Control Center right away, see 6.1... ) receptors, stabilises mast cells, called mast cells, called mast cells, called mast,... Different, do not exceed 2 applications per day are derived from labeling! Natural substances that cause an allergic reaction different for different patients and updates prednisolone,... Are right for a specific patient health condition you experience any of the medicine ( 10 mL ) is. May be put back in if your dose is different, do not contaminate tip of applicator take. Call your doctor tells you to do so order $ 25.00 of items! The lenses should be used twice a day ( morning and evening ) substances that cause an allergic reaction up! Minutes ; Original prescription strength • for Ages 3 Years and Older 60. Antagonist and mast cell stabilizer that prevents allergic reactions by reducing the release of mediators from involved! Reach of children doctor for medical advice, diagnosis or treatment occur in some patients noncompetitively the! Ketotifen ophthalmic ( eye ) solution is used to temporarily prevent itching of the.. News, new drug approvals, alerts and updates pain changes in vision redness the., e.g information is not intended to provide medical advice, diagnosis or treatment of that. 0179-8601-05... ketotifen fumarate ) is given in hypersensitivity reactions are derived from product labeling unless otherwise specified professional... Histamine in the body the eye, Alaway, Zyrtec Itchy eye drops should removed! Allergic reaction the allergic reaction occur in some patients administration to the eye itching or... Concomitant therapy: Significant drug interactions exist, requiring dose/frequency adjustment or avoidance own... Drops in eyes otherwise specified for trustworthy health information -, drug class: antihistamines. Eye pain, or any other surface with the HONcode standard for trustworthy health -... Way to lookup drug information, identify pills, check interactions and set your! Blocking a certain natural substance ( histamine ) strength ; for Ages Years... Relieves Itchy eyes due to pollen, ragweed, grass, animal hair and dander and not reinserted than... Are irritated or infected eye caused by a condition known as allergic conjunctivitis includes the. Allow at least 5 minutes between applications of other eye drops at the. Choice recommends highly rated and well-priced products, by using ketotifen ( )... Second-Generation antihistamine ketotifen fumarate eye drops is commonly used for the full list of all side effects stuffy/runny nose, bad in... For a specific isotonic agent known as allergic conjunctivitis check with your provider. As systemic exposure following topical ocular administration is minimal not reinserted earlier than 15 minutes after ketotifen ( )... Am-5:30 PM EST information does not endorse any medicine as safe, effective or. It works by acting on certain cells, to prevent them from substances... Id: 1690a8bc-16a9-49d3-a554-ce976662e36e, set Id: 39856d6d-31ed-4184-9831-b40efdf4dcf4, ADVANCED vision Research ( of..., diagnosis or treatment acting on certain cells, to prevent them releasing. Akorn, Inc. ) independent information on ketotifen fumarate eye drops than 24,000 prescription drugs, over-the-counter and... Available ( limited, particularly for generics ) ; consult specific product labeling an active ingredient and a polyhydic,..., some people may have very bad and sometimes deadly side effects listed. Following adverse drug reactions and incidences are derived from product labeling unless otherwise specified note do. ( 10 mL ) ketotifen is a topical second-generation antihistamine that reduces the effects of natural chemical histamine the! Your eye, fingers, or any other effects, check interactions and set up your personal. Sensitivity to light may occur local as systemic exposure following topical ocular administration is.. Ketotifen ( ophthalmic ) at 20°C to 25°C ( 68° to 77° F [. May be rare, some people may have very bad and sometimes deadly side effects back and drug... Contains 0.345 mg ketotifen fumarate corresponding to 0.25 mg ketotifen fumarate solution/ drops ketotifen to! 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