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</html>";s:4:"text";s:7098:"It has become a very personal issue for a whole lot of people in this country. Science tries to answer the question: How? How do cells act in the body? The difference which renders it possible to obtain 'submaximal' contractions from a whole skeletal muscle but not from a whole heart is not a difference in the functional capabilities of the two types of cell; it depends upon the fact that cardiac muscle cells are connected one with another, whereas skeletal muscle cells are isolated by their sarcolemma. I remember vividly my student days, spending hours at the light microscope, turning endlessly the micrometric screw, and gazing at the blurred boundary which concealed the mysterious ground substance where the secret mechanisms of cell life might be found. But we have the strongest of indications that, in the stroma of the resting nucleus, every one of the chromosomes that enters the nucleus survives as a well-defined region; and as the cell prepares for its next division this region again gives rise to the same chromosome (Theory of the Individuality of the Chromosomes). Any ambiguity, any tendency to wander from the matter at hand, will introduce grave hazards for the cells, and even more for the host in which they live. The body is a cell state in which every cell is a citizen. Sitewide search within all Today In Science History pages. Trained in the tradition of the theory of solutions, many a biochemist tends, even today, to regard the cell as a bag of enzymes. Address to the American Association for the Advancement of Science in Philadelphia (28 Dec 1904), as quoted in 'Americans of Future Will Have Best Brains'. One of these grows rapidly, creating the human body of the individual with all its organs, and dies only with the individual. Your cell phone has already replaced your camera, your calendar and your alarm clock. One is in physics, where leading theorists are striving, with the help of experimentalists, to devise a single mathematical theory that embraces all the basic phenomena of matter and energy. When bacteria invade the blood stream, the white corpuscles, like the ants defending the nest, are drawn mechanically to the infected spot, and will die defending the human cell colony. It needs a green light and a red light as well. Though we may extend our thought beyond imaginable space, yet compared with reality we bring to birth mere atoms. It appears unlikely that the role of the genes in development is to be understood so long as the genes are considered as dictatorial elements in the cellular economy. Cell genetics led us to investigate cell mechanics. The elementary parts of all tissues are formed of cells in an analogous, though very diversified manner, so that it may be asserted, that there is one universal principle of development for the elementary parts of organisms, however different, and that this principle is the formation of cells. But each day, nevertheless, when you try to get started you have to transmogrify, transpose yourself; you have to go through some kind of change from being a normal human being, into becoming some kind of slave. They have memories, they must be divided into countless thousands of groups, most are workers, there are directing groups. By virtue of this ability of theirs to replicate, these genesor, if you prefer, genetic materialcontained in the nuclear chromosomes and in whatever other portion of the cell manifests this property, such as the chloroplastids of plants, must form the basis of all the complexities of living matter that have arisen subsequent to their own appearance on the scene, in the whole course of biological evolution. As water-soluble polar compounds with no proper melting points they were extremely difficult to handle by the classic techniques of organic chemistry, and were accordingly very discouraging substances to early workers. Our children will enjoy in their homes electrical energy too cheap to meter. ), Surely the mitochondrion that first entered another cell was not thinking about the future benefits of cooperation and integration; it was merely trying to make its own living in a tough Darwinian world. The change from protogene to protozoan was probably the most complex that has occurred in evolution, and it may well have taken as long as the change from protozoan to man. It may well be asked why the chemistry of these groups of compounds was not further advanced, particularly since we recognize today that they occupy a central place in the history of the living cell. The brain of man, like that of all animals is double, being parted down its centre by a thin membrane. Two prisoners whose cells adjoin communicate with each other by knocking on the wall. A stem cell is essentially a blank cell capable of becoming another, more differentiated cell-type in the body, such as a skin cell, a muscle cell or a nerve cell. A cell of a higher organism contains a thousand different substances, arranged in a complex system. As quoted by Kitta MacPherson in 'Exploring Epigenetics: President Shirley Tilghman in the Classroom,' even Mozart started out this way. There is a finite number of species of plants and animalseven of insectsupon the earth. On this view the genes are highly specific chemically, and thus called into play only under very specific conditions; but their morphological effects, if any, rest on quantitative influences of immediate or remote products on growth gradients, which are resultants of all that has gone on before in the organism. I discovered (no, not me: my team) the function of sugar nucleotides in cell metabolism. on these expanded membranes [butterfly wings] Nature writes, as on a tablet, the story of the modifications of species, so truly do all changes of the organisation register themselves thereon. I can't beat you. If this theory is correct, it should be possible to record the action potential between an electrode inside a nerve fibre and the conducting fluid outside it. Address given at the 1913 meeting of the Koninklijke Akademie van Wetenschappen in Amsterdam. With the aid of energy derived from the sun it has built up the most complicated systems to be found in the universeliving organisms. Life arose as a living molecule or protogene, the progression from this stage to that of the ameba is at least as great as from ameba to man. The Nobel Prize for Chemistry: Introductory Address'. We use psychic bullets and kill each other cell by cell. It is not so much that the cells make the plant; it is rather that the plant makes the cells. Since disease originates in the elementary cell, the organization and microscopic functions of which reproduce the general organization exactly and in all its relationships, nothing is more suited to simplifying the work of classification and of systematic division than to take the elementary cell as the basis of division. But spend the people's money on proven blood cord, bone marrow, germ cell, and adult cell research. The history of the universe is in every one of us. 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