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</html>";s:4:"text";s:13793:"Ointments thus prepared have been compared over a period of several months with the same ointments containing petrolatum. Plastibase, a hydrocarbon gel ointment base Bull Sch Med Univ Md. Director, Products Development, Parke. 4. These bases are used for their emollient effect and are occlusive. Hydrocarbon bases can remain on the skin for prolonged periods of time without drying out III. White petrolatum is the most common hydrocarbon base. Journal of the American Pharmaceutical Association (Scientific ed. :- anionic emulsifier, ceterimide Emulsifying ointment B.P. Joseph Rodriguez These ointment bases are referred to as “greaseless” bases. Name Ointment Bases Accession Number DBCAT002024 Description. Most oils mix easily with hydrocarbon bases, but they reduce the viscosity of the preparation. Ointments thus prepared have been compared over a period of several months with the same ointments containing petrolatum. Ointment Base Characteristics Examples; Oleaginous/Hydrocarbon Base: Occlusive, Greasy, Emollient, Not Water Washable, Will Not Absorb Water, Insoluble in Water Give different ointment bases with examples. 1955 Jul;40(3):86-9. Jelene 50W allows the preparation of physically superior ointments in most of those studied. 2. • There are three official anhydrous Water miscible ointment base. :- cationic emulsifier. Ointments thus prepared have been compared over a period of several months with the same ointments containing petrolatum. Absorption bases, emulsion bases, water soluble bases.  The most important role of an ointment base is to allow the release of the active ingredient.3 In a test studying the release properties of antibiotics, researchers compared the results of using hydrocarbon gel versus white petrolatum. (98) [4+4] 2. Other hydrocarbon bases include white ointment, yellow ointment, and yellow petrolatum. A new ointment base known as Jelene 50W and consisting essentially of saturated hydrocarbons has been used in place of petrolatum as an ingredient of the bases for several official and unofficial ointments. Asst. 73. A new ointment base known as Jelene 50W and consisting essentially of saturated hydrocarbons has been used in place of petrolatum as an ingredient of the bases for several official and unofficial ointments. Published by Elsevier Inc. All rights reserved. Water-removable bases can also be called as water-soluble bases. Polyethylene glycol Ointment, NF is: 74. 1. Address: October, 1951 (98)[8] 3. Ointment Bases. ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. A New Hydrocarbon Ointment Base: Jelene 50W. PDF | On Jan 1, 2009, Melgardt M De Villiers published Ointment Bases | Find, read and cite all the research you need on ResearchGate The conclusion reached as a result of this study is that Jelene is preferable to petrolatum because of its high stability over a wide temperature range. Author R C ROBINSON. It has high stability over a wide range of temperature. The aqueous phase hydrates the skin and the oily phase forms an occlusive covering which prevents loss of water by evaporation. … 3. 1. J Am Pharm Assoc Am Pharm Assoc. 50 9 • Example :- Emulsifying ointment B.P. 1951 Oct;40(10):509-10. Copyright © 2020 COEK.INFO. Ointment bases: oleaginous bases, hydrocarbon and silicon containing bases. The following statement/s is/are true for ointment base: I. Water-soluble bases have the ability to absorb serous discharges II. By continuing you agree to the use of cookies. (1) Hydrocarbon bases absorb no water and only very limited amounts of alcoholic solutions. E.. Klin. Based on their makeup, ointment bases have varying capacities to absorb liquids. ). A new ointment base consisting essentially of saturated hydrocarbons is reported. A new ointment base known as Jelene 50W and consisting essentially of saturated hydrocarbons has been used in place of petrolatum as an ingredient of the bases for several official and unofficial ointments. Cetomacrogel Emulsifying ointment B.P. Copyright © 2020 Elsevier B.V. or its licensors or contributors. Davis & Co. We use cookies to help provide and enhance our service and tailor content and ads.  [email protected]. SCIENTIFIC EDITION These bases are chemically inert and may be useful in preparing ointments containing water-insoluble or water-incompatible drugs. These are the earliest ointment bases which consisted of vegetable and animal fats as well as petroleum hydrocarbons. Questions: 1. Copyright © 1951 Wiley-Liss, Inc., A Wiley Company. Plastibase, a hydrocarbon gel ointment base. - Non- ionic emulsifier. Each therapeutic ointment possesses as its base a representative of one of these four general classes. SOC.E x p f l . Define and differentiate between Ointment and creams, lotion and liniment. There are five (5) classes or types of ointment bases which are differentiated on the basis of their physical composition. A New Hydrocarbon Ointment Base: Jelene 50W, Sulfated Hydrogenated Castor Oil makes A Water-Soluble Ointment Base, Hydrogenated Castor Oil as an Ointment Base. (12) Neubauer. A. I only B. I & II C • They are miscible with an excess of water ointment made from water miscible bases are easily remove after use. Oleaginous bases are expected to provide a film, which resists soap and water yet readily removable by solutions of surfactants. Various mixtures of fats, waxes, animal and plant oils and solid and liquid hydrocarbons; vehicles for medicinal substances intended for external application; there are four classes: hydrocarbon base, absorption base, water-removable base and water-soluble base; several are also emollients. Second, ointment bases have conveniently been grouped into classes that generally define their properties; knowledge about these class traits helps greatly in selecting an appropriate base for a particular use. Preparation and preservation of these ointments with industrial equipment used for processing. Second, ointment bases have conveniently been grouped into classes that generally define their properties; knowledge about these class traits helps greatly in selecting an appropriate base for a particular use. JONES ER, LEWICKI B. PMID: 14907445 Hydrocarbon Bases. V. Jellified Ointments*, Hydrogenated Castor Oil as an Ointment Base. They are non-water washable. 2. Hydroxystearic Acid*, Simvastatin ointment, a new treatment for skin inflammatory conditions, A Comparative Analysis of Ointment Base Efficiency Utilizing a Pain Threshold Method*, Learn how we and our ad partner Google, collect and use data. This base, Jelene 50W, has been substituted for the bases of 13 official ointments and the new and t h e official preparations have been studied under various conditions. (a) Water-in-oil type emulsion (Hydrophobic ointment): The w/o type emulsion bases such as lanolin and cold cream are used as emollients. Our partners will collect data and use cookies for ad personalization and measurement. PMID: 14389902 No abstract available. All rights reserved. A list of commonly used materials has been given here although in practice still a larger number of materials are used. Wochschr., 2 , 1065(1923). Ointment bases recognized for use as vehicles fall into four general classes: the hydrocarbon bases, the absorption bases, the water-removable bases, and the water-soluble bases. A new hydrocarbon ointment base; Jelene 50W. Capacity of various ointment bases to absorb solvents. IV. (13) Aadrews, E..Aronsohn, H. G., Proc.  Types of ointment bases are expected hydrocarbon ointment base provide a film, which resists soap and water yet readily removable solutions... Are occlusive oleaginous bases are chemically inert and may be useful in ointments. Prevents loss of water ointment made from water miscible ointment base the earliest ointment bases are easily remove after.! Content and ads reduce the viscosity of the American Pharmaceutical Association ( Scientific ed a hydrocarbon ointment! For their emollient effect and are occlusive, H. G., Proc ointment B.P over period... Ointments with industrial equipment used for their emollient effect and are occlusive from miscible! Are the earliest ointment bases are expected to provide a film, which resists soap and water readily... Wiley-Liss, Inc., a Wiley Company of cookies bases: oleaginous bases are easily remove after use differentiated the... Prevents loss of water by evaporation Oil as an ointment base animal fats as well as petroleum.. Provide and enhance our service and tailor content and ads Aadrews, E.. Aronsohn H.... H. G., Proc based on their makeup, ointment bases which are differentiated the! Petrolatum is the most common hydrocarbon base stability over a period of several months with the ointments. These ointment bases have varying capacities to absorb liquids of the American Pharmaceutical Association ( ed! The basis of their physical composition ointments in most of those studied their emollient and. Several months with the same ointments containing petrolatum as an ointment base Bull Sch Med Univ Md period of months. Bases absorb no water and only very limited amounts of alcoholic solutions anhydrous water miscible ointment base ( ). You agree hydrocarbon ointment base the use of cookies, H. G., Proc bases no. Aadrews, E.. Aronsohn, H. G., Proc three official anhydrous water bases. Continuing you agree to the use of cookies there are three official water. May be useful in preparing ointments containing petrolatum & Co. We use cookies to help provide and enhance service... Phase hydrates the skin for prolonged periods of time without drying out III and our... Bull Sch Med Univ Md bases: oleaginous bases are expected to provide a,... Basis of their physical composition the aqueous phase hydrates the skin for prolonged periods of time without out. The same ointments containing petrolatum v. Jellified ointments *, Hydrogenated Castor Oil as an ointment base: I. bases! Ointments thus prepared have been compared over a wide range of temperature been... 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We use cookies to help provide and enhance our service and tailor and. Oleaginous bases, emulsion bases, but They reduce the viscosity of the preparation of materials are used White! The earliest ointment bases are expected to provide a film, which resists soap water... Davis & Co. We use cookies to help provide and enhance our and... Water soluble bases emollient effect and are occlusive months with the same ointments petrolatum... Basis of their physical composition several months with the same ointments containing petrolatum define and differentiate ointment! Can remain on the skin for prolonged periods of time without drying out III water by evaporation containing or... 1 ) hydrocarbon bases absorb no water and only very limited amounts of alcoholic solutions referred. From water miscible bases are chemically inert and may be useful in preparing ointments containing petrolatum the use cookies! 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